** Estrostep FE contains the progestin norethindrone acetate (this progestin typically has a higher androgen potency). Therefore, although Estrostep FE follows more of a high androgenic/low estrogenic pattern, this brand is a triphasic pill that was actually designed to help prevent breakthrough bleeding while attempting to keep hormone exposure as low as possible. Estrostep FE is a good example as to why the information in this chart should be viewed more in terms of being general guidelines, and may not always hold from one woman to another.
The following agents or drugs or medications increase or hasten the bio degradation of Loette contraceptive pill in the body, thereby reducing its contraceptive efficacy and increase the risk of pregnancy:
These include:-Ritonavir, Rifampicin, Rifabutin, Barbiturates, Primidone, Phenylbutazone, Phenytoin, Dexamethasone, Griseofulvin, Modafinil, Topiramate, Certain Antibiotics Like Ampicillin and Tetracycline, St. John's wort On the other hand, drugs that increase the concentrations of Loette in the blood and thereby predispose to higher side effect profiles include Atorvastatin, vitamin C, Acetaminophen, Indinavir and Fluconazole among others.