There are also many drug interactions . Patients must read in detail the enclosed data sheet(s) of the medicine. For example, the azole antifungals such as ketoconazole or itraconazole can be both substrates and inhibitors of the P-glycoprotein , which (among other functions) excretes toxins and drugs into the intestines.  Azole antifungals also are both substrates and inhibitors of the cytochrome P450 family CYP3A4 ,  causing increased concentration when administering, for example, calcium channel blockers , immunosuppressants , chemotherapeutic drugs , benzodiazepines , tricyclic antidepressants , macrolides and SSRIs .
Before you turn a blind eye to this solution realize that undecylenic acid is just a fancy name for an organic, unsaturated fatty acid that is naturally derived from natural castor oil. Castor oil (for those unfamiliar) is a vegetable oil that is derived from castor beans. In the manufacturing process, the castor oil chemical bonds are broken down to create undecylenic acid. According to , it is a recognized natural fungicide that is FDA approved in over-the-counter medications for skin disorders or problems http:///mtm/undecylenic-acid- . It can also be found as the active ingredient in medications for skin infections and relives itching, burning and irritation.