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DDE has been shown to be toxic to rats at  mg/kg. [4] DDE and its parent, DDT, are reproductive toxicants for certain birds species, and major reasons for the decline of the bald eagle , [5] brown pelican [6] peregrine falcon , and osprey . [7] These compounds cause egg shell thinning in susceptible species, which leads to the birds’ crushing their eggs instead of incubating them, due to the latter’s lack of resistance. [8] Birds of prey , waterfowl , and song birds are more susceptible to eggshell thinning than chickens and related species , and DDE appears to be more potent than DDT. [7]

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