An additional well-known and well-established fact is that all anabolic steroids exhibit negative impacts on cholesterol levels, as well as cardiovascular strain in the human body. This involves the reduction of HDL (the good cholesterol) and increases of LDL (the bad cholesterol). The result of such changes involves an increased risk of arteriosclerosis , and the degree to which these changes occur for the worse are usually dose-dependent (with higher doses increasing the negative changes and the risks). Other factors that affect these negative cholesterol changes are: duration of use, and route of administration. It is imperative considering this particular effect of anabolic steroids on the body that any users of anabolic steroids no matter the preparation (oral or injectable) take exquisite care to make proper adjustments in their dietary habits which favor positive cholesterol maintenance and changes, especially when running cycles of anabolic steroids .